Health

Making Rabies Visible: Delhi’s Push for Mandatory Disease Notification

Context: The Delhi government has announced its decision to declare human rabies a notifiable disease under the Epidemic Diseases Act, 1897. This move mandates compulsory reporting of all suspected, probable, and confirmed rabies cases by public and private healthcare providers. The decision aligns with the National Action Plan for Dog-Mediated Rabies Elimination (NAPRE), which aims to eliminate rabies in India by 2030, and follows similar steps already taken by 20 Indian states.

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What Does “Notifiable Disease” Mean?

A notifiable disease is one that must be reported to government health authorities upon diagnosis or suspicion.

  • Legal obligation: Reporting is mandatory, with penalties for non-compliance under public health laws.
  • Timelines: Urgent cases require reporting within 24 hours, while routine cases must be reported within three days.
  • Authority: States notify diseases under state laws or the Epidemic Diseases Act, while the Centre can mandate nationwide notification (e.g., tuberculosis in 2012).
  • Surveillance: All reported cases are integrated into the Integrated Disease Surveillance Programme (IDSP) for real-time monitoring.

Why Notifying Rabies Matters

  • Early Detection: Mandatory reporting helps identify outbreaks quickly and track spatial clustering.
  • Public Health Response: Enables timely interventions such as post-exposure prophylaxis, contact tracing, and animal control measures.
  • Resource Allocation: Assists governments in planning vaccine supply, immunoglobulin distribution, and workforce deployment.
  • Accountability: Improves transparency and reduces under-reporting of a highly fatal disease.

About Rabies

Rabies is a viral disease of the central nervous system that is almost 100% fatal once symptoms appear, but is entirely preventable with timely vaccination.

  • Causative agent: Rabies virus (RABV).
  • Transmission: Mainly through saliva via dog bites or scratches; not transmitted through blood, urine, or faeces.
  • Reservoir: Domestic dogs account for nearly 99% of global human rabies cases.
  • Incubation period: Usually 1–3 months, but can exceed one year.
  • Global goal: The WHO-led “Zero by 30” initiative aims to eliminate dog-mediated human rabies deaths by 2030.

Rabies Burden in India

  • India accounts for about 36% of global rabies deaths, making it the world’s most affected country.
  • The National Rabies Control Programme (NRCP) provides free vaccines, rabies immunoglobulin, surveillance, and awareness campaigns.
  • NAPRE adopts a One Health approach, integrating human health, animal health, and municipal governance to eliminate rabies.

Significance of Delhi’s Decision

Declaring rabies a notifiable disease marks a shift from reactive treatment to proactive surveillance. It strengthens epidemiological tracking, supports India’s global elimination commitments, and underscores the role of data-driven governance in public health.

If effectively implemented, Delhi’s step can serve as a model for urban rabies control across India.

Organ Transplantation in India: Bridging the Gap Between Law and Lives

Context: Despite nearly three decades of the Transplantation of Human Organs and Tissues Act (THOTA), 1994, India’s deceased organ donation ecosystem remains underdeveloped. According to The Hindu, the deceased donor rate continues to be critically low, highlighting systemic, legal, and operational constraints.

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Organ Donation Performance in India

India’s deceased organ donation rate stood at 0.77 per million population (pmp) in 2023, starkly lower than Spain’s 49.38 pmp, the global leader. An estimated 5 lakh Indians die annually due to non-availability of organs. Although over 50,000 Brainstem Death (BSD) cases are medically eligible each year, only 700–900 deceased donors are realised.

Further, 85% of transplants rely on living donors, unlike developed countries where 70–80% are from deceased donors. Alarmingly, only 2–3% of ICU deaths undergo BSD certification. The apnea test is mandatory for confirming irreversible loss of brainstem function and is central to BSD determination.

Legal and Institutional Framework

The THOTA, 1994 provides the statutory backbone for organ transplantation in India. It:

  • Recognises Brainstem Death as legal death, enabling deceased donation.
  • Regulates living donations, transplant hospitals, and penalises organ trade.
  • Prescribes certification and consent norms (Form 10 for BSD declaration; Form 8 for consent).

Institutional mechanisms include:

  • NOTTO: National apex body for organ allocation, registry, and coordination.
  • ROTTO: Regional coordination across States.
  • SOTTO: State nodal agencies for training, hospital networking, and awareness.

Key Challenges

  • Low BSD Utilisation: Massive gap between eligible and certified BSD cases.
  • Dual Death Certificate Ambiguity: Issuance of both BSD and cardiac death certificates causes legal uncertainty and delays.
  • Restricted Certification Locations: BSD certification allowed only in registered transplant centres, excluding over 90% of public ICU hospitals.
  • Doctor Approval Bottleneck: Less than 8% of government doctors are authorised for BSD certification.
  • Consent Timing Errors: Families often approached before formal BSD certification, leading to 60–70% refusal rates in major public hospitals.

Way Forward

  • Universal BSD Certification: Permit all ICU-equipped hospitals to certify BSD, as practiced in Spain.
  • Single Death Certificate Rule: Recognise BSD as the final legal time of death; Kerala’s 2020 order is a best practice.
  • Trained Transplant Coordinators: Deploy certified counsellors in ICUs; Tamil Nadu’s model increased donations by over 400%.
  • Digital BSD Registry: Establish a real-time, integrated BSD and organ availability platform linked with NOTTO and SOTTO.

Healthcare Sector of India: Progress, Gaps and Policy Direction

Context: The Union Government informed Parliament that India’s doctor–population ratio stands at 1:811, better than the WHO norm of 1:1000, highlighting quantitative progress in healthcare availability while masking structural challenges.

India’s healthcare system has undergone significant expansion over the last decade, driven by a shift towards universal health coverage, preventive care, and infrastructure strengthening. However, challenges related to financing, equity, and quality of care continue to demand policy attention.

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Current Status of India’s Healthcare System

Public health expenditure has increased gradually to 1.9% of GDP (FY 2023–24), yet remains below the National Health Policy (2017) target of 2.5% by 2025. While financial protection has improved, Out-of-Pocket Expenditure (OOPE) still accounts for 39.4% of total health spending, exposing households to catastrophic health shocks.

India’s improved doctor–population ratio reflects expanded medical education capacity, but rural–urban disparities, uneven specialist distribution, and shortages in public facilities persist. The disease profile has also shifted decisively towards non-communicable diseases (NCDs), which account for over 60% of deaths, necessitating long-term, preventive, and primary-care-driven interventions.

A major structural reform has been the transition to Comprehensive Primary Health Care (CPHC) through the establishment of over 1.7 lakh Health and Wellness Centres, now renamed Ayushman Arogya Mandirs (AAMs). These centres focus on NCD screening, mental health, geriatric care, and preventive services.

Government Measures and Initiatives

The flagship Ayushman Bharat programme anchors India’s healthcare reforms through two pillars.

First, PM-JAY provides health insurance coverage of ₹5 lakh per family per year for secondary and tertiary care to about 12 crore vulnerable families, reducing financial hardship.

Second, Ayushman Arogya Mandirs strengthen grassroots healthcare delivery.

The National Health Mission (NHM) continues to support states in expanding healthcare access, improving maternal and child health, and addressing regional disparities.

Complementing this, the PM Ayushman Bharat Health Infrastructure Mission (PM-ABHIM) focuses on building critical care blocks, disease surveillance units, and public health laboratories to enhance pandemic preparedness.

To tackle medicine affordability, the Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP) has expanded access to quality generic medicines through thousands of Janaushadhi Kendras, directly contributing to the reduction in OOPE.

Way Forward

India’s healthcare priorities must now focus on increasing public spending, addressing human-resource imbalances, strengthening urban and rural primary care, and integrating digital health solutions.

Greater emphasis on preventive care, mental health, and geriatric services is essential to manage the rising NCD burden.

Overall, India’s healthcare sector reflects meaningful progress, but achieving equitable, affordable, and quality healthcare for all will require sustained fiscal commitment, cooperative federalism, and systemic reforms.

WHO Releases Guidelines on GLP-1 Use for Obesity Treatment

The World Health Organisation (WHO) has issued its first-ever global guidelines on the use of GLP-1 (Glucagon-Like Peptide-1) receptor agonists for treating obesity, marking a major shift in international clinical and public-health policy. These medicines—originally developed for diabetes—have shown significant weight-loss benefits but raise concerns regarding affordability, long-term safety, and unequal access.

GLP-1 drugs mimic the natural hormone that increases insulin secretion, suppresses appetite, slows gastric emptying, and reduces glucagon levels. Popular therapies include liraglutide, semaglutide, and tirzepatide.

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Key Features of the WHO Guidelines

1. Conditional Recommendations

WHO issued two conditional guidelines owing to limited long-term evidence and substantial cost barriers:

  • GLP-1 Therapies for Adults: Medicines such as semaglutide and tirzepatide may be used for long-term treatment, except in pregnant women.
  • Behavioural Interventions Mandatory: Drug therapy must be accompanied by structured dietary counselling, physical activity programmes, and regular follow-up.

2. Obesity as a Chronic Disease

The guidelines adopt a lifelong care model, positioning obesity as a chronic metabolic condition requiring sustained clinical management rather than short-term weight-loss attempts.

3. Three-Pillar Strategy

WHO recommends a multilevel approach that integrates:

  • Population-level measures (healthy food policies, regulation of marketing, active-living environments)
  • Targeted screening and early interventions
  • Lifelong, person-centred care, including pharmacotherapy where appropriate

4. Health Equity Concerns

The guidelines highlight the limited global capacity to manufacture GLP-1 drugs and project that less than 10% of people with obesity worldwide will benefit by 2030 due to cost and supply constraints.

Global and Indian Burden of Obesity

Obesity is defined by WHO as BMI ≥ 30 in adults.

  • Global Burden (2024): Over 1 billion people affected; 3.7 million deaths linked to obesity-related conditions.
  • India (NFHS-5): 24% of women and 25% of men are overweight or obese.
  • Projections: India may exceed 163 million adults with obesity by 2030, nearly doubling current levels.

Obesity’s rapid rise, combined with the expanding but inequitable availability of GLP-1 therapies, underscores the need for integrated public-health measures and affordable access strategies.

World AIDS Day 2025: Overcoming Disruption, Transforming the AIDS Response

Context: World AIDS Day is observed every year on 1 December, and the 2025 global theme is “Overcoming disruption, transforming the AIDS response.” The theme underscores the need to rebuild resilient HIV services disrupted by pandemics, inequalities, and funding constraints, while accelerating progress toward global elimination targets.

About World AIDS Day

World AIDS Day was established in 1988 by the World Health Organisation (WHO) and later guided by UNAIDS, becoming the first international health awareness day.
Its key objectives include:

  • Raising awareness about HIV prevention, testing, and treatment
  • Combating stigma and discrimination
  • Mobilising global solidarity toward ending AIDS as a public health threat

The observance aligns with the UNAIDS 95-95-95 target and SDG 3.3, which aims to end AIDS by 2030.

UNAIDS 95-95-95 Goal

  • 95% of people living with HIV diagnosed
  • 95% of those diagnosed on antiretroviral therapy (ART)
  • 95% of those on ART achieving viral suppression

India’s AIDS Response

India’s AIDS programme is led by the National AIDS Control Organisation (NACO) under the Ministry of Health and Family Welfare.

Institutional and Policy Framework

  • Implemented through National AIDS and STD Control Programme (NACP) Phases I–V
  • Focus areas: awareness, prevention, testing expansion, free ART, and targeted interventions
  • HIV & AIDS (Prevention and Control) Act 2017:
    • Prohibits discrimination
    • Ensures confidentiality
    • Mandates informed consent for HIV testing and treatment

Key Initiatives

  • Test & Treat Policy (ART for all diagnosed patients)
  • Mission Sampark to re-engage patients lost to follow-up
  • Expansion of Integrated Counselling and Testing Centres (ICTCs) and ART centres nationwide

Impact

Between 2010 and 2021:

  • New HIV infections fell by ~46%
  • AIDS-related deaths dropped by ~77%

These improvements reflect enhanced treatment access, targeted outreach, and community-led approaches.

Understanding HIV–AIDS

Cause

  • HIV attacks CD4+ T-cells, progressively weakening immunity.
  • Untreated infection may progress to Acquired Immunodeficiency Syndrome (AIDS).

Transmission

  • Unprotected sexual contact
  • Contaminated needles
  • Unsafe blood transfusion
  • Mother-to-child transmission

Treatment

  • Antiretroviral Therapy (ART) reduces viral load, prevents progression to AIDS, and lowers transmission risk—forming the basis of the “treatment-as-prevention” model.

India Status

  • India has an estimated 2.4 million people living with HIV.
  • The epidemic is concentrated among high-risk groups:
    • Sex workers
    • Men who have sex with men (MSM)
    • People who inject drugs (PWID)
    • Transgender persons
    • Migrant labour
    • Truckers

Conclusion

World AIDS Day 2025 reinforces the global commitment to restore disrupted services, advance equity, and strengthen community-led interventions as India moves toward eliminating AIDS as a public health threat. With legal safeguards, expanded ART access, and strong institutional frameworks, India continues to make significant strides in prevention and treatment.

UN & WHO Warn of Rising Cervical Cancer Deaths

The United Nations (UN) and the World Health Organization (WHO) have issued a global alert on rising cervical cancer deaths as the world observed the first World Cervical Cancer Elimination Day on 17 November 2025. The day was officially designated by the 78th World Health Assembly (WHA) to accelerate international commitments towards eliminating cervical cancer as a public health threat.

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About Cervical Cancer

Cervical cancer develops in the cervix— the lower part of the uterus—mainly due to persistent infection with high-risk Human Papillomavirus (HPV).
Importantly, cervical cancer is highly preventable, and early vaccination combined with periodic screening drastically reduces mortality.

Global Burden

  • It is the 4th most common cancer in women globally, causing one death every two minutes (WHO).
  • In 2022, the world recorded 660,000 new cases and 350,000 deaths.
  • The South-East Asia region contributes nearly one-fourth of the global burden.
  • 94% of global deaths occur in low- and middle-income countries, primarily due to limited access to screening, late detection and treatment shortages.

India’s Burden

India remains one of the worst-affected countries:

  • India contributed around one-fifth of global cases and nearly a quarter of global deaths (2020).
  • Cervical cancer is the second most common cancer among Indian women, after breast cancer.
  • Screening levels remain extremely low: <10% of women have ever been screened; only 2% have undergone screening in the last five years (NFHS-5).

About Human Papillomavirus (HPV)

HPV is a double-stranded DNA virus infecting skin and mucosal surfaces.

  • 200+ types exist—classified as low-risk (warts) and high-risk (cancer-causing).
  • HPV types 16 & 18 account for ~99% of cervical cancer cases.

HPV Vaccination & Prevention Strategies

Vaccines

Six HPV vaccines are globally available, all targeting high-risk HPV 16 and 18.
India developed its first indigenous quadrivalent HPV vaccine (qHPV) called Cervavac, manufactured by the Serum Institute of India, with support from the Department of Biotechnology.

Target Group

Vaccination is most effective for girls aged 9–14 years, before sexual exposure.

WHO Elimination Strategy (2020)

To eliminate cervical cancer by 2030, WHO recommends the 90-70-90 targets:

  • 90% of girls fully vaccinated by age 15
  • 70% of women screened at ages 35 & 45
  • 90% of women with cervical disease receive treatment

India’s Policy Steps

  • NTAGI has recommended integrating the HPV vaccine into the Universal Immunisation Programme (UIP).
  • The 2024–25 Union Budget approved phased free vaccination for girls aged 9–14, marking a major step toward national cervical cancer elimination.

Cervical cancer is among the few cancers that can be prevented, detected early, and cured. Scaling up vaccination, expanding screening, and strengthening health systems are essential for India and the world to meet the 2030 elimination goal.

Govt Amends VOPPA Order to Tighten Edible Oil Regulations

Context: The Ministry of Consumer Affairs, Food & Public Distribution has issued the Vegetable Oil Products, Production and Availability (Regulation) Amendment Order, 2025 (VOPPA 2025) to enhance regulatory oversight and transparency in India’s edible oil sector.

The VOPPA Order, originally notified in 2011 under the Essential Commodities Act, 1955, governs the production, distribution, and trade of edible oils in India.

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Objective of the Amendment

The amendment aims to:

  • Prevent hoarding and artificial shortages,
  • Improve transparency in production and trade data,
  • Strengthen enforcement against misreporting, and
  • Ensure consumer protection through stable and fair prices.

Key Provisions of VOPPA (Amendment) Order, 2025

  • Mandatory Online Registration: All edible oil producers, refiners, and traders must register digitally with state and central authorities.
  • Monthly Digital Reporting: Real-time data submission on stocks, production, and prices.
  • Alignment with Essential Commodities Act (1955): Ensures definitional uniformity for better policy enforcement.
  • Enhanced Penalties: Tighter action against hoarding, under-reporting, and stock manipulation.

Significance:

These reforms strengthen market surveillance, ensure accurate data flow for policy interventions, and improve food security resilience amid global supply disruptions.

India’s Edible Oil Sector: Overview

  • Consumption: India is the world’s second-largest consumer of edible oils after China. Per capita consumption surpasses ICMR’s recommended intake levels.
  • Import Dependence: Imports account for 55–60% of total demand, making India the largest global importer—ahead of China and the U.S.
  • Composition of Imports:
    • Palm Oil: ~56% (mostly from Indonesia & Malaysia)
    • Soybean Oil: ~27%
    • Sunflower Oil: ~16%
  • Domestic Production: Key oilseeds—soybean (34%), rapeseed–mustard (31%), and groundnut (27%)—constitute over 90% of domestic output.
  • Structural Issues: Low productivity due to small rainfed farms, outdated processing tech, and limited irrigation.

Government Initiatives

  • NMEO–Oil Palm (2021): Focuses on self-reliance in palm oil production in the North-East and Andaman–Nicobar Islands.
  • NMEO–Oilseeds (2024): Promotes yield improvement and secondary oil sources (rice bran, cottonseed) using modern technologies.

Way Forward

  • Develop strategic edible oil reserves to cushion price shocks.
  • Promote research and hybrid seeds for higher oil content.
  • Enhance domestic value chains through cooperatives and agri-startups.
  • Strengthen digital traceability systems for transparent supply chains.

Conclusion

The VOPPA 2025 Amendment represents a critical reform for ensuring edible oil availability, stabilising prices, and reducing India’s heavy import dependence — aligning with national goals of food security and Atmanirbhar Bharat.

Trachoma: Fiji Eliminates a Preventable Cause of Blindness

Context: Fiji has become the 26th country in the world to eliminate Trachoma as a public health problem, as validated by the World Health Organization (WHO). This marks a major step towards achieving the global goal of ending trachoma by 2030 under the WHO NTD Roadmap.

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What is Trachoma?

Trachoma is a bacterial eye infection caused by Chlamydia trachomatis. It spreads through:

  • Direct contact with the eyes, eyelids, or nasal secretions of an infected person.
  • Indirect contact via contaminated towels, clothing, or flies that have come into contact with discharge from infected eyes or nose.

If untreated, repeated infections lead to scarring of the inner eyelid, causing eyelashes to turn inward and scratch the cornea, ultimately leading to irreversible blindness.

Signs and Symptoms

  • Redness and irritation of eyes
  • Watery or purulent discharge
  • Swelling of eyelids
  • Blurred vision
  • Discharge from the nose

Treatment and Prevention

  • Drugs:
    • Azithromycin (oral)
    • Tetracycline (eye ointment)
  • Preventive Measures:
    • Improved facial cleanliness and sanitation
    • Access to clean water
    • Control of disease-carrying flies

WHO’s SAFE Strategy

The WHO recommends the SAFE Strategy to eliminate trachoma as a public health problem:

SAFE StrategyDescription
SurgeryTo correct advanced stages of trachoma causing eyelid deformities
AntibioticsTo clear infection (e.g., Azithromycin)
Facial cleanlinessPromotes hygiene to reduce transmission
Environmental improvementAccess to clean water, sanitation, and reduced fly population

Global and Indian Context

  • According to WHO, 150 million people are still at risk of trachoma globally, mainly in Africa, the Middle East, and parts of Asia.
  • The disease primarily affects poor, rural communities lacking sanitation and healthcare access.
  • India has made significant progress under the National Programme for Control of Blindness and Visual Impairment (NPCBVI), though surveillance continues in endemic areas.

Significance

Fiji’s success demonstrates the effectiveness of community-level health interventions, strong surveillance, and cross-sector collaboration in eliminating neglected tropical diseases. It also strengthens global momentum toward Universal Eye Health and the WHO’s 2030 NTD Roadmap.

Rising Antibiotic Resistance: A Global Health Emergency

Context: The World Health Organization’s Global Antibiotic Resistance Surveillance Report (2025) warns that nearly 1 in 6 bacterial infections worldwide in 2023 were resistant to antibiotics. Between 2018–2023, resistance rose in over 40% of pathogen–antibiotic combinations, with an annual increase of 5–15%, signaling an accelerating global health emergency.

What is Antimicrobial Resistance (AMR)?

Antimicrobial Resistance (AMR) occurs when microorganisms (bacteria, viruses, fungi, parasites) evolve to resist the effects of drugs designed to kill them.

  • Example: Multi-Drug-Resistant Tuberculosis (MDR-TB) — caused by Mycobacterium tuberculosis resistant to both isoniazid (INH) and rifampicin (RMP).
  • AMR makes infections harder to treat, increases hospital stays, and raises mortality risk.

Key Findings from WHO Report (2025):

  • Scale of Resistance:
    Globally, 16% of lab-confirmed infections were antibiotic-resistant in 2023. The highest rates are reported from South-East Asia and the Eastern Mediterranean, where 1 in 3 infections show resistance.
  • Most Affected Pathogens (8 major bacteria):
    E. coli, Klebsiella pneumoniae, Acinetobacter spp., Salmonella spp., Shigella spp., Staphylococcus aureus, Streptococcus pneumoniae, Neisseria gonorrhoeae.
  • Drug Resistance Pattern:
    Over 40% of E. coli and 55% of Klebsiella pneumoniae strains are resistant to 3rd-generation cephalosporins, a mainline antibiotic group.
  • Data Gaps:
    Nearly 48% of countries did not report sufficient data to the Global AMR Surveillance System (GLASS), reflecting weak diagnostic capacity and reporting infrastructure.

India’s Perspective

India faces one of the highest burdens of AMR globally.

  • Causes: Overuse of antibiotics, self-medication, poor infection control, and use of antibiotics in livestock.
  • Initiatives:
    • National Action Plan on AMR (2017–2025).
    • AMR Surveillance & Research Network (ICMR).
    • “One Health” approach integrating human, animal, and environmental health.

Way Forward

  • Stewardship: Rational antibiotic prescription and public awareness.
  • Surveillance: Strengthen global and national reporting systems.
  • Research: Promote new antibiotics, vaccines, and alternatives like phage therapy.
  • Global Cooperation: Coordinated policy response under WHO and UN frameworks.

Conclusion

Antibiotic resistance is not just a medical challenge—it is a societal threat jeopardizing modern medicine. Strengthening surveillance, promoting responsible use, and fostering global partnerships remain key to reversing the tide of AMR.

DRAVYA Portal: Digitising India’s Ayurvedic Knowledge Base

Context: The Ministry of Ayush, through the Central Council for Research in Ayurvedic Sciences (CCRAS), has launched the DRAVYA PortalDigitized Retrieval Application for Versatile Yardstick of AYUSH Substances. The portal serves as India’s largest digital repository of Ayurvedic ingredients and products, aimed at modernising and standardising traditional medicinal knowledge.

In its first phase, the DRAVYA Portal will catalogue information on 100 key medicinal substances, integrating both classical Ayurvedic knowledge and modern scientific validation.

About DRAVYA Portal

  • Full Form: Digitized Retrieval Application for Versatile Yardstick of AYUSH Substances (DRAVYA)
  • Developed by: Central Council for Research in Ayurvedic Sciences (CCRAS), under the Ministry of Ayush.
  • Objective: To create a comprehensive and dynamic database on Ayurvedic raw materials, formulations, and therapeutic properties.
  • Coverage: Combines information from classical Ayurvedic texts, scientific literature, and field studies.
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Key Features:

  • AI-Ready Framework: Designed to integrate with the Ayush Grid and upcoming digital health initiatives for evidence-based research.
  • Comprehensive Search: Users can explore medicinal substances used across Ayurveda and other AYUSH systems.
  • Multi-Domain Data: Each entry includes details on pharmacotherapeutics, botany, chemistry, pharmacology, and safety.
  • QR Code Integration: Enables standardised information display in medicinal plant gardens, herbariums, and research repositories.
  • Dynamic and Open Access: The portal continuously evolves with verified data from modern research and classical sources.

Significance:

  • Knowledge Preservation: Bridges traditional Ayurvedic wisdom with modern scientific validation.
  • Standardisation: Facilitates evidence-based policymaking and quality assurance in herbal drugs.
  • Research & Innovation: Supports AI-driven drug discovery and formulation development.
  • Global Collaboration: Positions India as a leader in digital traditional medicine data architecture under the One Health framework.

Way Forward

Integration with Pharmacopoeia Commission for Indian Medicine & Homoeopathy (PCIM&H) for standard drug codification.

Expansion to cover 5000+ medicinal substances over subsequent phases.
Promotion of interdisciplinary research between Ayurveda, biotechnology, and pharmacology sectors.

E-Cigarettes and the Rising Health Risks

Context: According to WHO’s first global estimate of e-cigarette use (2024), teenagers are nine times more likely to vape than adults, raising major public health concerns worldwide.

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About E-Cigarettes:

  • E-cigarettes are battery-operated devices that heat a liquid into an inhalable aerosol.
  • The liquid typically contains nicotine, propylene glycol, glycerin, flavouring agents, and other chemicals.
  • Known as vape pens, ENDS (Electronic Nicotine Delivery Systems), or ENNDS (Electronic Non-Nicotine Delivery Systems).
  • Though they may not contain tobacco, they often deliver addictive nicotine doses similar to conventional cigarettes.

WHO’s Key Findings (2024):

  • 15 million teenagers (13–15 yrs) use e-cigarettes globally.
  • Youth are 9× more likely to vape than adults.
  • Total vapers: over 100 million, including 86 million adults (mostly in high-income nations).
  • Tobacco use declined from 1.38 billion (2000)1.2 billion (2024).
  • Regional trends:
    • Southeast Asia: Male tobacco use fell from 70% → 37% (2000–2024).
    • Europe: Now the highest tobacco prevalence (24.1%) globally.

Legal Framework in India:

The Prohibition of Electronic Cigarettes Act, 2019

  • Complete Ban: Prohibits production, import, export, transport, sale, distribution, storage, and advertisement of e-cigarettes.
  • Penalties:
    • Manufacture/sale/advertisement → Imprisonment up to 1 year or ₹1 lakh fine (first offence); up to 3 years or ₹5 lakh (repeat offence).
    • Storage → Up to 6 months jail or ₹50,000 fine.
  • Exemption: Permitted only for research and testing purposes.

Implementation Challenges in India:

  • Online Accessibility: Over 60% of e-cigarette products remain available on e-commerce platforms (Voluntary Health Association of India, 2023).
  • Youth Appeal: Flavoured variants and influencer marketing target adolescents.
  • Lack of Support Systems: Only 1 in 5 tobacco users has access to quitting support or therapy (GATS 2022).
  • Product Evasion: New disposable or flavoured devices enter India through unregulated channels.

Way Forward:

Digital Surveillance: Deploy AI-based systems to monitor illegal online sales (like the EU’s Track & Trace model).

Youth Awareness: Launch anti-vaping campaigns under the National Tobacco Control Programme (NTCP)—similar to New Zealand’s Vape-Free Schools.
Quit Support Expansion: Strengthen helplines like mCessation, which has helped over 3 million users attempt quitting.

Inter-Agency Coordination: Form a Nicotine Product Enforcement Task Force involving MoHFW, IT Ministry, and Customs.

Health Ministry Advisory on Cough Syrups for Children

Context: The Directorate General of Health Services (DGHS) under the Ministry of Health and Family Welfare has issued a fresh advisory to all States and Union Territories on the rational use of cough syrups in children. The move comes after reports of child deaths in Rajasthan and Madhya Pradesh, allegedly linked to syrups containing Dextromethorphan.

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About Dextromethorphan

  • Dextromethorphan (DXM) is a cough suppressant used in many over-the-counter syrups.
  • It acts on the brain’s cough centre to reduce coughing but can cause serious side effects in children — such as drowsiness, breathing difficulty, and accidental overdose.
  • Long-term effects on the developing brain remain unclear, making it unsafe for paediatric use.

Key Guidelines Issued by DGHS

  • Avoid Routine Use: Most coughs in children are self-limiting and do not require medication.
  • Age Restriction: Cough syrups must not be prescribed for children below two years.
  • Clinical Evaluation: For older children, use only after proper medical evaluation — with accurate dosage and for the shortest possible duration.
  • Avoid Polypharmacy: Syrups containing multiple drug combinations should be avoided.
  • Non-Drug Remedies: Encourage hydration, steam inhalation, and rest as safer alternatives.
  • Pharma Compliance: Manufacturers must strictly follow Good Manufacturing Practices (GMP) and use pharmaceutical-grade excipients.

Contamination and Safety Investigations

  • The Health Ministry clarified that syrups linked to the incidents were free from diethylene glycol (DEG) and ethylene glycol (EG) — two highly toxic industrial chemicals responsible for several global poisoning incidents.
  • In Rajasthan, the formulation in question contained Dextromethorphan, which is not recommended for children under national and WHO safety standards.

Chemical Toxicity Explained

  • Diethylene Glycol (DEG): Used in antifreeze; causes kidney failure, neurological damage, and death.
  • Ethylene Glycol (EG): Another toxic antifreeze component that leads to acute kidney injury if ingested.

Significance

  • Reinforces paediatric drug safety and the need for rational prescription practices.
  • Aims to prevent avoidable child fatalities from inappropriate or contaminated medicines.
  • Strengthens pharmaceutical quality control and public health accountability.

Conclusion:

The DGHS advisory highlights India’s growing vigilance in paediatric pharmacovigilance. Rational use of medicines, strict enforcement of safety standards, and public awareness are key to protecting children from preventable drug-related tragedies.