- Born in Midnapore in West Bengal.
- Public speeches of Aurobindo Ghose and Sister Nivedita prompted him to join the freedom struggle during the Swadeshi Movement.
- In 1905, during the Partition of Bengal, he became an active volunteer in the freedom movement.
- Khudiram was all of 15 when he first courted arrest for distributing pamphlets against the British administration.
- In 1908, Khudiram joined Anushilan Samiti and under Aurobindo Ghose and his brother Barindra Ghose, he got fully involved in anti-British activities. Its leaders then decided to appoint Khudiram Bose and Prafulla Kumar Chaki to conduct the mission of assassinating Douglas H Kingsford through a bomb attack.
- However, it was discovered later that the carriage was carrying the wife and daughter of a barrister called Pringle Kennedy, and Kingsford had escaped yet another attempt on his life.
- Khudiram was sentenced to death (making him one of the youngest revolutionaries in India to be hanged by the British) and Prafulla Kumar Chaki committed suicide.